Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence
Jalali Elnaz, Ferneini Elie M., Rengasamy Kandasamy, Tadinada Aditya,
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( Jalali Elnaz ) - Eliray Oral and Maxillofacial Radiology Consulting Services
( Ferneini Elie M. ) - University of Connecticut Department of Craniofacial Sciences Division of Oral and Maxillofacial Surgery
( Rengasamy Kandasamy ) - University of Connecticut School of Dental Medicine Section of Oral and Maxillofacial Radiology
( Tadinada Aditya ) - University of Connecticut School of Dental Medicine Section of Oral and Maxillofacial Radiology
Abstract
Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC.
키워드
Carcinoma; Squamous Cell; Odontogenic Cysts; Maxilla; Cell Transformation; Neoplastic
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